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International Journal of Clinical and Experimental Medicine Research

The Toxoplasma Rubella Cytomegalovirus Herpes (Torch) Infection Risk Factor of Sensorineural Hearing Loss in Children

Author:Bambang Udji Djoko Rianto*, Bondan Herwindo, Anggoro Eka Raditya, Ashadi Prasetyo Date:December 21,2017 Hits:

Abstract

Objective: Sensorineural hearing loss in children can cause speech language, social communication and developmental delays. Sensorineural hearing loss in children can be caused by congenital and acquired (infectious and non-infectious) factors.:This study aimed to determine the most significant risk factors for the sensorineural hearing loss in children. Methods: This study used a case-control design. Study samples were patients at Dr. Sardjito General Hospital Yogyakarta between January 2014 until April 2015. Inclusion criteria for the case group were sensorineural hearing loss (SNHL), and aged 0-5 years, while the control group was normal hearing children. Exclusion criterion for both groups was incomplete data. Diagnostic criteria were based on Oto-Acoustic Emission (OAE) and Brainstem Evoke Response Audiometry (BERA) results.There were 31 samples in the case group and 31 samples in the control group.Results:Bivariate statistical analysis showed that the TORCH (Toxoplasma Rubella Cytomegalovirus Herpes) variable was a significant risk factor for SNHL (OR 11.94; 95% CI: 2.41-59.02), while hyperbilirubinemia (OR: 0.75; 95% CI: 0.26-2.14), low birth weight (OR: 2.36; 95% CI: 0.81-6.91), neonatal asphyxia (OR: 2.28; 95% CI: 0.94-8.47), and prematurity (OR: 1.70; 95% CI: 0.52-5.55) were not significant risk factors.Bivariate statistical analysis showed that the TORCH (Toxoplasma Rubella Cytomegalovirus Herpes) variable was a significant risk factor for SNHL (OR 11.94; 95% CI: 2.41-59.02).Based on multivariate analysis we found TORCH infection was a significant risk factor for the incidence of SNHL in children (OR 15.63; 95% CI: 2.84-85.95). Conclusions:Based on the results of this study, TORCH infection is a statistically significant risk factor for the incidence of sensorineural hearing loss in children. Early screening for at-risk children is highly recommended.

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The Toxoplasma Rubella Cytomegalovirus Herpes (Torch) Infection Risk Factor of Sensorineural Hearing Loss in Children 
Bambang Udji Djoko Rianto1*, Bondan Herwindo1, Anggoro Eka Raditya1, Ashadi Prasetyo1
1Department of Ear Nose Throat-Head and Neck Surgery, Faculty of Medicine, Universitas Gadjah Mada/ DR. Sardjito General Hospital 
Yogyakarta, Indonesia
*Corresponding to: Bambang Udji Djoko Rianto, Department of Ear Nose Throat-Head and Neck Surgery, Faculty of Medicine, Universitas Gadjah Mada/ DR. Sardjito General Hospital Yogyakarta, Indonesia 
How to cite this paper: Bambang Udji Djoko Rianto, Bondan Herwindo, Anggoro Eka Raditya, Ashadi Prasetyo1 (2017) The Toxoplasma Rubella Cytomegalovirus Herpes (Torch) Infection Risk Factor of Sensorineural Hearing Loss in Children. International Journal of Clinical and Experimental Medicine Research, 1(3), 16-21.
http://dx.doi.org/10.26855/ijcemr.2017.03.001
DOI: 10.26855/ijcemr.2017.03.001
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