Bo Sheng1, Jingjing Liu2,*
1Department of tumor surgery, Jingzhou first people's Hospital, Jingzhou 434000, Hubei, China.
2Department of operating room, Jingzhou first people's Hospital, Jingzhou 434000, Hubei, China.
*Corresponding author: Jingjing Liu
Abstract
Objective: To observe and analyze the clinical value of laparoscopic cholecystectomy at different times in patients with acute cholecystitis after puncture and drainage. Methods: A total of 80 patients with acute cholecystitis admitted to our hospital from May 2020 to October 2022 were enrolled. All patients were treated with acute cholecystitis puncture and drainage and laparoscopic cholecystectomy. They were divided into two groups by random number table method (short-term group and long-term group, with 40 cases in each group).The short-term group was treated with laparoscopic cholecystectomy within 1 months after the operation of acute cholecystitis puncture and drainage, and the long-term group was treated with laparoscopic cholecystectomy 1 months after the operation. The perioperative general conditions, inflammatory status, liver function and the incidence of perioperative adverse events were compared between the two groups. Results: The perioperative operation time, postoperative drainage time and perioperative hospital stay in the long-term group were shorter than those in the recent group, and the intraoperative blood loss was less than that in the recent group, and the differences were statistically significant (P < 0.05). After operation, the levels of C-reactive protein, interleukin-6 and other inflammatory factors in the two groups were lower than those before operation, and the indicators in the long-term group were lower than those in the short-term group, and the differences were statistically significant (P < 0.05). The incidence of perioperative adverse events in long-term group was lower than that in short-term group, and the difference was statistically significant (P < 0.05).After operation, the liver function indexes such as alanine aminotransferase and total bilirubin in the two groups were lower than those before operation, and the indexes in the long-term group were lower than those in the short-term group, and the differences were statistically significant (P < 0.05). Conclusion: Long-term laparoscopic cholecystectomy for patients with acute cholecystitis after puncture and drainage is helpful to improve the surgical effect and safety, and promote the improvement of early postoperative liver function and inflammatory status.
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