International Journal of Clinical and Experimental Medicine Research

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Article http://dx.doi.org/10.26855/ijcemr.2023.01.005

Meta-analysis of Risk Factors for Liver Damage in Newly Diagnosed Patients with Hyperthyroidism

Shufang Wang1, Liangyu Tang1, Jingjing Sun1, Zefen Lu2,*, Sufang Zhang1, Siwei Gong1

1Chengde Medical University, Chengde 067000, China.

2Cangzhou People's Hospital, Cangzhou 061000, China.

*Corresponding author: Zefen Lu

Published: February 3,2023

Abstract

Objective: To systematically evaluate the risk factors of liver damage in newly diagnosed patients with hyperthyroidism and provide a clinical basis for the diagnosis and treatment of liver injury in hyperthyroidism. Methods: Pubmed, Embase, The Cochrane Library, CNKI, VIP and other databases were searched to collect the risk factors of hepatic damage in newly diagnosed hyperthyroidism patients published up to May 2020. Library until May 2020. Two researchers independently screened the literature, extracted data, and evaluated the risk of bias in the included studies, and Meta-analysis was performed by RevMan 5.3 software. Results: A total of 18 documents were included, with a total of 2637 cases and 1884 controls. Meta-analysis results show: age, course of disease, thyroid weight, FT4, TRAb, TGAb, TPOAb are all risk factors for hepatic injury in newly diagnosed patients with hyperthyroidism. Conclusion: While age, course of disease, thyroid weight, FT4, TRAb, TGAb and TPOAb are risk factors for liver damage in newly diagnosed patients with hyperthyroidism, gender has nothing to do with them.

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How to cite this paper

Meta-analysis of Risk Factors for Liver Damage in Newly Diagnosed Patients with Hyperthyroidism

How to cite this paper: Shufang Wang, Liangyu Tang, Jingjing Sun, Zefen Lu, Sufang Zhang, Siwei Gong. (2023) Meta-analysis of Risk Factors for Liver Damage in Newly Diagnosed Patients with Hyperthyroidism. International Journal of Clinical and Experimental Medicine Research7(1), 26-32.

DOI: http://dx.doi.org/10.26855/ijcemr.2023.01.005