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The Research Progress in Postpartum Depression in the Context of COVID-19

Date: February 7,2023 |Hits: 310 Download PDF How to cite this paper

Zhong Zhang, Zhefeng Liu*

Shaanxi University of Chinese Medicine, Xianyang, Shaanxi 712046, China.

*Corresponding author: Zhefeng Liu


COVID-19 first began in December 2019 and has spread across the globe for nearly three years, and so far COVID-19 has caused more than 600 million infections and more than 6 million deaths worldwide. In terms of human health, COVID-19 as a respiratory disease, in addition to the direct damage to physical health caused by the disease itself, also has a direct or indirect impact on people's mental health, according to WHO reports that in the first year of the COVID-19 epidemic, the incidence of mental illnesses such as depression and anxiety increased by more than 25%, increasing the number of patients by about 1 billion people, and postpartum women are one of the most Postpartum women are one of the most important populations, with postpartum depression being the most common. Studies from around the world have shown that the prevalence of COVID-19 affects postpartum women and postpartum depression to varying degrees and shows a diversity of influencing factors. In this paper, the effects of COVID-19 on postpartum women and postpartum depression around the world and the related responses and effects are reviewed in the hope of providing a reference for clinical management of postpartum depression in the COVID-19 setting.


[1] Gavin, N. I., Gaynes, B. N., Lohr, K. N., Meltzer-Brody, S., Gartlehner, G., & Swinson, T. (2005). Perinatal depression: a systematic review of prevalence and incidence. Obstetrics and gynecology, 106(5 Pt 1), 1071–1083. 


[2] Vesga-López, O., Blanco, C., Keyes, K., Olfson, M., Grant, B. F., & Hasin, D. S. (2008). Psychiatric disorders in pregnant and postpartum women in the United States. Archives of general psychiatry, 65(7), 805–815. 


[3] Payne, J. L., & Maguire, J. (2019). Pathophysiological mechanisms implicated in postpartum depression. Frontiers in neuroendocrinology, 52, 165–180. https://doi.org/10.1016/j.yfrne.2018.12.001.

[4] Sudhinaraset, M., Landrian, A., Mboya, J., & Golub, G. (2022). The economic toll of COVID-19: A cohort study of prevalence and economic factors associated with postpartum depression in Kenya. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 158(1), 110–115. 


[5] Obata, S., Miyagi, E., Haruyama, Y., Umazume, T., Kobashi, G., Yoshimi, A., Hishimoto, A., Kurasawa, K., Suzuki, Y., Ikeda, T., Kimura, T., & Yamada, H. (2021). Psychological stress among pregnant and puerperal women in Japan during the coronavirus disease 2019 pandemic. The journal of obstetrics and gynaecology research, 47(9), 2990–3000. 


[6] Vatcheva, T., Mostaert, A., Van Ingelgem, V., Henrion, E., & Legros, L. (2021). Impact of COVID-19 pandemic on postpartum depression among mothers of extreme and early preterm infants. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 155(3), 

490–495. https://doi.org/10.1002/ijgo.13859.

[7] McFarland, M. J., McFarland, C. A. S., Hill, T. D., & D'Oria, R. (2021). Postpartum Depressive Symptoms during the Beginning of the COVID-19 Pandemic: An Examination of Population Birth Data from Central New Jersey. Maternal and child health journal, 25(3), 353–359. https://doi.org/10.1007/s10995-020-03116-w.

[8] Gustafsson, H. C., Young, A. S., Doyle, O., Nagel, B. J., Mackiewicz Seghete, K., Nigg, J. T., Sullivan, E. L., & Graham, A. M. (2021). Trajectories of perinatal depressive symptoms in the context of the COVID-19 pandemic. Child development, 92(5), e749–e763. https://doi.org/10.1111/cdev.13656.

[9] Fallon, V., Davies, S. M., Silverio, S. A., Jackson, L., De Pascalis, L., & Harrold, J. A. (2021). Psychosocial experiences of postnatal women during the COVID-19 pandemic. A UK-wide study of prevalence rates and risk factors for clinically relevant depression and anxiety. Journal of psychiatric research, 136, 157–166. https://doi.org/10.1016/j.jpsychires.2021.01.048. 

[10] Guvenc, G., Yesilcinar, İ., Ozkececi, F., Öksüz, E., Ozkececi, C. F., Konukbay, D., Kok, G., & Karasahin, K. E. (2021). Anxiety, depression, and knowledge level in postpartum women during the COVID-19 pandemic. Perspectives in psychiatric care, 57(3), 1449–1458. https://doi.org/10.1111/ppc.12711.

[11] Safi-Keykaleh, M., Aliakbari, F., Safarpour, H., Safari, M., Tahernejad, A., Sheikhbardsiri, H., & Sahebi, A. (2022). Prevalence of postpartum depression in women amid the COVID-19 pandemic: A systematic review and meta-analysis. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 157(2), 240–247. https://doi.org/10.1002/ijgo.14129.

[12] Hessami, K., Romanelli, C., Chiurazzi, M., & Cozzolino, M. (2022). COVID-19 pandemic and maternal mental health: a sys-tematic review and meta-analysis. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 35(20), 4014–4021. https://doi.org/10.1080/14767058.2020.1843155.

[13] Chen, Q., Li, W., Xiong, J., & Zheng, X. (2022). Prevalence and Risk Factors Associated with Postpartum Depression during the COVID-19 Pandemic: A Literature Review and Meta-Analysis. International journal of environmental research and public health, 19(4), 2219. https://doi.org/10.3390/ijerph19042219.

[14] Liang, P., Wang, Y., Shi, S., Liu, Y., & Xiong, R. (2020). Prevalence and factors associated with postpartum depression during the COVID-19 pandemic among women in Guangzhou, China: a cross-sectional study. BMC psychiatry, 20(1), 557. https://doi.org/10.1186/s12888-020-02969-3.

[15] Silverman, M. E., Burgos, L., Rodriguez, Z. I., Afzal, O., Kalishman, A., Callipari, F., Pena, Y., Gabay, R., & Loudon, H. (2020). Postpartum mood among universally screened high and low socioeconomic status patients during COVID-19 social restrictions in New York City. Scientific reports, 10(1), 22380. https://doi.org/10.1038/s41598-020-79564-9. 

[16] Hiiragi, K., Obata, S., Misumi, T., Miyagi, E., & Aoki, S. (2021). Psychological stress associated with the COVID-19 pandemic in postpartum women in Yokohama, Japan. The journal of obstetrics and gynaecology research, 47(6), 2126–2130. https://doi.org/10.1111/jog.14776.

[17] Viaux-Savelon, S., Maurice, P., Rousseau, A., Leclere, C., Renout, M., Berlingo, L., Cohen, D., & Jouannic, J. M. (2022). Impact of COVID-19 lockdown on maternal psychological status, the couple's relationship and mother-child interaction: a prospective study. BMC pregnancy and childbirth, 22(1), 732. https://doi.org/10.1186/s12884-022-05063-6.

[18] Gaillard, A., Le Strat, Y., Mandelbrot, L., Keïta, H., & Dubertret, C. (2014). Predictors of postpartum depression: prospective study of 264 women followed during pregnancy and postpartum. Psychiatry research, 215(2), 341–346. https://doi.org/10.1016/ j.psychres.2013.10.003.

[19] Boekhorst, M. G. B. M., Muskens, L., Hulsbosch, L. P., Van Deun, K., Bergink, V., Pop, V. J. M., & van den Heuvel, M. I. (2021). The COVID-19 outbreak increases maternal stress during pregnancy, but not the risk for postpartum depression. Archives of women's mental health, 24(6), 1037–1043. https://doi.org/10.1007/s00737-021-01104-9.

[20] Lewkowitz, A. K., Schlichting, L., Werner, E. F., Vivier, P. M., Kahn, L. G., & Clark, M. A. (2022). Risk factors for new-onset postpartum depression or anxiety symptoms during the COVID-19 pandemic. American journal of obstetrics & gynecology MFM, 4(1), 100502. https://doi.org/10.1016/j.ajogmf.2021.100502.

[21] Pereira, D., Wildenberg, B., Gaspar, A., Cabaços, C., Madeira, N., Macedo, A., & Pereira, A. T. (2022). The Impact of COVID-19 on Anxious and Depressive Symptomatology in the Postpartum Period. International journal of environmental research and public health, 19(13), 7833. https://doi.org/10.3390/ijerph19137833.

[22] Bajaj, M. A., Salimgaraev, R., Zhaunova, L., & Payne, J. L. (2022). Rates of self-reported postpartum depressive symptoms in the United States before and after the start of the COVID-19 pandemic. Journal of psychiatric research, 151, 108–112. https://doi.org/10.1016/j.jpsychires.2022.04.011.

[23] Shuman, C. J., Peahl, A. F., Pareddy, N., Morgan, M. E., Chiangong, J., Veliz, P. T., & Dalton, V. K. (2022). Postpartum depression and associated risk factors during the COVID-19 pandemic. BMC research notes, 15(1), 102. https://doi.org/10. 1186/s13104-022-05991-8.

[24] Njoroge, W. F. M., White, L. K., Waller, R., Forkpa, M., Himes, M. M., Morgan, K., Seidlitz, J., Chaiyachati, B. H., Barzilay, R., Kornfield, S. L., Parish-Morris, J., Rodriguez, Y., Riis, V., Burris, H. H., Elovitz, M. A., & Gur, R. E. (2022). Association of COVID-19 and Endemic Systemic Racism With Postpartum Anxiety and Depression Among Black Birthing Individuals. JAMA psychiatry, 79(6), 600–609. https://doi.org/10.1001/jamapsychiatry.2022.0597.

[25] Erten, Ö., Biyik, İ., Soysal, C., Ince, O., Keskin, N., & Tascı, Y. (2022). Effect of the Covid 19 pandemic on depression and mother-infant bonding in uninfected postpartum women in a rural region. BMC pregnancy and childbirth, 22(1), 227. https://doi.org/10.1186/s12884-022-04580-8

[26] Hui, P. W., Ma, G., Seto, M. T. Y., & Cheung, K. W. (2021). Effect of COVID-19 on delivery plans and postnatal depression scores of pregnant women. Hong Kong medical journal = Xianggang yi xue za zhi, 27(2), 113–117. https://doi.org/10.12809/ hkmj208774.

[27] Tariq, N., Habib, M., Tariq, A., Noor, M., & Jamal, A. (2021). Impact of Covid-19 On Post Natal Mental Health. Journal of Ayub Medical College, Abbottabad: JAMC, 33(4), 659–663.

[28] Mariño-Narvaez, C., Puertas-Gonzalez, J. A., Romero-Gonzalez, B., & Peralta-Ramirez, M. I. (2021). Giving birth during the COVID-19 pandemic: The impact on birth satisfaction and postpartum depression. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 153(1), 83–88. https://doi.org/10. 1002/ijgo.13565.

[29] Tsuno, K., Okawa, S., Matsushima, M., Nishi, D., Arakawa, Y., & Tabuchi, T. (2022). The effect of social restrictions, loss of social support, and loss of maternal autonomy on postpartum depression in 1 to 12-months postpartum women during the COVID-19 pandemic. Journal of affective disorders, 307, 206–214. https://doi.org/10.1016/j.jad.2022.03.056.

[30] Suzuki S. (2022). Changes in psychological status of postpartum women due to the COVID-19 pandemic in Japan. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 35(15), 3012–3013. https://doi.org/ 10.1080/14767058.2020.1814250.

[31] Gluska, H., Mayer, Y., Shiffman, N., Daher, R., Elyasyan, L., Elia, N., Weiner, M. S., Miremberg, H., Kovo, M., Biron-Shental, T., Helpman, L., & Gabbay-Benziv, R. (2021). The use of personal protective equipment as an independent factor for developing depressive and post-traumatic stress symptoms in the postpartum period. European psychiatry: the journal of the Association of European Psychiatrists, 64(1), e34. https://doi.org/10.1192/j.eurpsy.2021.29.

[32] Karavadra, B., Stockl, A., Prosser-Snelling, E., Simpson, P., & Morris, E. (2020). Women's perceptions of COVID-19 and their healthcare experiences: a qualitative thematic analysis of a national survey of pregnant women in the United Kingdom. BMC pregnancy and childbirth, 20(1), 600. https://doi.org/10.1186/s12884-020-03283-2.

[33] Gemmill, A. W., Oliva, J. L., Ericksen, J., Holt, C., Holt, C. J., & Milgrom, J. (2022). Web-based treatment for depression in pregnancy: a feasibility study of Mum2BMoodBooster. BMC psychiatry, 22(1), 476. 


[34] Van Lieshout, R. J., Layton, H., Savoy, C. D., Brown, J. S. L., Ferro, M. A., Streiner, D. L., Bieling, P. J., Feller, A., & Hanna, S. (2021). Effect of Online 1-Day Cognitive Behavioral Therapy-Based Workshops Plus Usual Care vs Usual Care Alone for Postpartum Depression: A Randomized Clinical Trial. JAMA psychiatry, 78(11), 1200–1207. 


[35] Pentland, V., Spilsbury, S., Biswas, A., Mottola, M. F., Paplinskie, S., & Mitchell, M. S. (2022). Does Walking Reduce Post-partum Depressive Symptoms? A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal of women's health (2002), 31(4), 555–563. https://doi.org/10.1089/jwh.2021.0296.

[36] Kim, H. B., & Hyun, A. H. (2022). Psychological and Biochemical Effects of an Online Pilates Intervention in Pregnant Women during COVID-19: A Randomized Pilot Study. International journal of environmental research and public health, 19(17), 10931. https://doi.org/10.3390/ijerph191710931.

[37] Hicks, L. M., Ou, C., Charlebois, J., Tarasoff, L., Pawluski, J., Roos, L. E., Hooykaas, A., Fairbrother, N., Carter, M., & Tomfohr-Madsen, L. (2022). Assessment of Canadian perinatal mental health services from the provider perspective: Where can we improve?. Frontiers in psychiatry, 13, 929496. https://doi.org/10.3389/fpsyt.2022.929496.

[38] COVID-19 Mental Disorders Collaborators. (2021). Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic. Lancet (London, England), 398(10312), 1700–1712. https://doi.org/10.1016/S0140-6736(21)02143-7.

[39] Mateus, V., Cruz, S., Costa, R., Mesquita, A., Christoforou, A., Wilson, C. A., Vousoura, E., Dikmen-Yildiz, P., Bina, R., Dominguez-Salas, S., Contreras-García, Y., Motrico, E., & Osório, A. (2022). Rates of depressive and anxiety symptoms in the perinatal period during the COVID-19 pandemic: Comparisons between countries and with pre-pandemic data. Journal of af-fective disorders, 316, 245–253. https://doi.org/10.1016/j.jad.2022.08.017.

[40] Sotoodeh Ghorbani, S., Taherpour, N., Bayat, S., Ghajari, H., Mohseni, P., & Hashemi Nazari, S. S. (2022). Epidemiologic characteristics of cases with reinfection, recurrence, and hospital readmission due to COVID-19: A systematic review and meta-analysis. Journal of medical virology, 94(1), 44–53. https://doi.org/10.1002/jmv.27281.

[41] Lechner-Scott, J., Levy, M., Hawkes, C., Yeh, A., & Giovannoni, G. (2021). Long COVID or post COVID-19 syndrome. Multiple sclerosis and related disorders, 55, 103268. https://doi.org/10.1016/j.msard.2021.103268.

How to cite this paper

The Research Progress in Postpartum Depression in the Context of COVID-19

How to cite this paper: Zhong Zhang, Zhefeng Liu. (2023) The Research Progress in Postpartum Depression in the Context of COVID-19. International Journal of Clinical and Experimental Medicine Research7(1), 92-98.

DOI: http://dx.doi.org/10.26855/ijcemr.2023.01.016

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