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International Journal of Food Science and Agriculture

ISSN Online: 2578-3475 ISSN Print: 2578-3467 CODEN: IJFSJ3
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ArticleOpen Access http://dx.doi.org/10.26855/ijfsa.2023.06.013

Serological Survey of Antibodies Against H5 and H7 Highly Pathogenic Avian Influenza Viruses in Shandong, China

Ruixue Xue#, Linlin Xing#, Zixin Jiang, Yujie Li, Cong Xu, Min Wang, Xianghua Kong, Yue Zhang*

Shandong Provincial Center for Animal Disease Control and Prevention (Shandong Provincial Center for Zoonoses Epidemiology Investigation and Surveillance), Jinan, Shandong, China.

#Both authors contributed equally to this work.

*Corresponding author: Yue Zhang

Published: July 30, 2023

Abstract

Research background: H5 and H7 highly pathogenic avian influenza (HPAI) outbreaks have caused huge economic losses among poultry farms which has prompted the Ministry of Agriculture and Rural Affairs of China to make immunization mandatory for both the H7 HPAI virus and H5 HPAI virus. Research methods: To determine the effects of immunization, 8,916 serum samples were collected from 294 flocks between 2019 and 2021 and subjected to serum antibody testing using the hemagglutination inhibition (HI) test. Our results showed that immune antibodies against H5 and H7 HPAI viruses exceeded 70% during the 3-year period, with layer farms and the eastern region having the most effective immunization. Greater focus on immune antibody monitoring is required in the southern, northwestern, and midland regions. Additionally, the immunization density and antibody monitoring efforts of broiler chicken farms should be further strengthened to enhance the overall prevention and control of major animal epidemic diseases.

Keyword

Highly pathogenic avian influenza (HPAI), poultry, serological survey, Shan-dong, immunization, H5/H7

References

[1] Centers for Disease Control and Prevention (CDC). Isolation of avian influenza A (H5N1) viruses from humans--Hong Kong, May-December 1997. Morbidity and Mortality Weekly Report. (December 19, 1997) 46:1204–1207.

[2] Alexander, D.J., and Brown, I.H. History of highly pathogenic avian influenza. Revue scientifique et technique (International Office of Epizootics). (Apr 1, 2009)28:19–38. doi:10.20506/rst.28.1.1856.

[3] Zhou, J., Wang, D., Gao, R., Zhao, B., Song, J., Qi, X., Zhang, Y., Shi, Y., Yang, L., Zhu, W., et al. Biological features of novel avian influenza A (H7N9) virus. Nature. (July 25, 2013) 499:500–503. doi:10.1038/nature12379.

[4] Shi, J., Deng, G., Ma, S., Zeng, X., Yin, X., Li, M., Zhang, B., Cui, P., Chen, Y., Yang, H., et al. Rapid evolution of H7N9 highly pathogenic viruses that emerged in China in 2017. Cell host & microbe. (October 10, 2018) 24:558–568.e7;.

doi:10.1016/j.chom.2018.08.006.

[5] World Organization for Animal Health (OIE). Avian influenza. In: Manual of diagnostic tests and vaccines for terrestrial animals. 6th ed. p 436–454; 2021. https://www.woah.org/en/international.

[6] Verhagen, J.H.; Fouchier, R.A.M.; Lewis, N. Highly Pathogenic Avian Influenza Viruses at the Wild–Domestic Bird Interface in Europe: Future Directions for Research and Surveillance. Viruses 2021, 13, 212. https://doi.org/10.3390/v13020212.

[7] Grant, M.; Bröjer, C.; Zohari, S.; Nöremark, M.; Uhlhorn, H.; Jansson, D.S. Highly Pathogenic Avian Influenza (HPAI H5Nx, Clade 2.3.4.4.b) in Poultry and Wild Birds in Sweden: Synopsis of the 2020–2021 Season. Vet. Sci. 2022, 9, 344. https://doi.org/10.3390/vetsci9070344.

[8] Venkatesh, D.; Brouwer, A.; Goujgoulova, G.; Ellis, R.; Seekings, J.; Brown, I.H.; Lewis, N.S. Regional Transmission and Reassortment of 2.3.4.4b Highly Pathogenic Avian Influenza (HPAI) Viruses in Bulgarian Poultry 2017/18. Viruses 2020, 12, 605. https://doi.org/10.3390/v12060605.

Copyright

© 2023 by the author(s).
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND) license, which permits non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited and is not modified or adapted.
https://creativecommons.org/licenses/by-nc-nd/4.0/

How to cite this paper

Serological Survey of Antibodies Against H5 and H7 Highly Pathogenic Avian Influenza Viruses in Shandong, China

How to cite this paper: Ruixue Xue, Linlin Xing, Zixin Jiang, Yujie Li, Cong Xu, Min Wang, Xianghua Kong, Yue Zhang. (2023) Serological Survey of Antibodies Against H5 and H7 Highly Pathogenic Avian Influenza Viruses in Shandong, China. International Journal of Food Science and Agriculture7(2), 252-256.

DOI: http://dx.doi.org/10.26855/ijfsa.2023.06.013