Heyang Wang1,*, Pan Liu2
1Wannan Medical College, Wuhu, Anhui, China.
2Wenzhou Medical University, Wenzhou, Zhejiang, China.
*Corresponding author: Heyang Wang
Abstract
This retrospective study aimed to investigate the clinical characteristics, prognosis, and treatment outcomes of liver metastatic cancer in patients with colorectal cancer. Medical records of patients diagnosed with colorectal cancer and concurrent hepatic metastatic cancer were collected from our hospital between October 2016 and June 2019. Among the 33 included patients, liver metastatic cancer accounted for 22.7% of the total diagnosed cases. The male-to-female ratio was 58:42, and the mean age was 55 years (range: 45-75 years). The liver metastatic carcinoma exhibited the same pathological type as the primary tumor, specifically adenosquamous cell tumor. Clinical manife-stations of liver metastatic cancer mainly included symptoms such as ascites, splenomegaly, and impaired liver function. The prognosis of patients with liver metastatic cancer was found to be poor, with a 5-year survival rate of approximately 30%. These findings highlight the high incidence of liver metastatic cancer in colorectal cancer patients and the worse prognosis compared to the primary tumor. It emphasizes the importance of regular liver examina-tions for colorectal cancer patients to facilitate early detection of liver metastases and the implementation of effective treatment strategies to improve patient survival rates.
References
[1] Ai X, Tao M, Wang H, et al. Analysis of survival factors after hepatic resection for colorectal cancer liver metastases: Does the R1 margin matter? [J]. Frontiers in Surgery, 2023, 9: 1020240.
[2] Kim K E, Bae S U, Jeong W K, et al. Impact of Preoperative Visceral Fat Area Measured by Bioelectrical Impedance Analysis on Clinical and Oncologic Outcomes of Colorectal Cancer [J]. Nutrients, 2022, 14(19): 3971.
[3] Nascimento A Q, Dantas D B, Melo G S, et al. Impact of sociodemographic factors and screening, diagnosis, and treatment strategies on colorectal cancer mortality in Brazil: A 20-year ecological study [J]. Plos one, 2022, 17(9): e0274572.
[4] Innominato P F, Cailliez V, Allard M A, et al. Impact of Preoperative Chemotherapy Features on Patient Outcomes after Hepa-tectomy for Initially Unresectable Colorectal Cancer Liver Metastases: A LiverMetSurvey Analysis [J]. Cancers, 2022, 14(17): 4340.
[5] Sawicki, T., Ruszkowska, M., Danielewicz, A., Niedźwiedzka, E., Arłukowicz, T., Przybyłowicz, K.E. A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis. Cancers, 2021, 13, 2025.
https://doi.org/10.3390/cancers13092025.
How to cite this paper
Analysis of Treatment and Survival Factors of Colorectal Cancer with Multiple Liver Metastases
How to cite this paper: Heyang Wang, Pan Liu. (2023) Analysis of Treatment and Survival Factors of Colorectal Cancer with Multiple Liver Metastases. International Journal of Clinical and Experimental Medicine Research, 7(3), 496-501.
DOI: http://dx.doi.org/10.26855/ijcemr.2023.07.035
