Drug Reposition: The Analysis of the Possibility of Using Aspirin for the Prevention of Cancers

Abstract

Aspirin is one of the oldest medicines that humans have used to treat a wide range of diseases. A good example is its use in the prevention of various tumors. Past studies have identified 11 types of cancer can be prevented by using aspirin. Within the past few decades, researchers have identified the mechanism through which aspirin prevents the development of cancer. Spe-cifically, researchers have found out that it has the potential to influence how cyclooxygenase-2(COX-2) is expressed in the body and its product, prostaglandin E2 (PGE2). These two compounds, COX-2 and PGE2, are essential in dictating the process of tumor cells. Past studies focusing on patients' health outcomes have also revealed that aspirin has the potential to influence the progression of cancer. However, there are limitations regarding the study and role of aspirin, such as side effects and inadequacy in research. Nonetheless, the progress of aspirin on a wide range of cancers continues to enhance patients' medical experiences and outcomes. This research reviewed several clinical trials related to aspirin and various types of cancers and analyzed the potential application of aspirin in cancer prevention. Several limitations, including the side effects of aspirin, appropriate dosage, and research constraints, have been taken into account.