Abstract
Objective: Sensorineural hearing loss in children
can cause speech language, social communication and developmental delays.
Sensorineural hearing loss in children can be caused by congenital and acquired
(infectious and non-infectious) factors.:This study aimed to determine the most significant risk factors for the sensorineural
hearing loss in children. Methods: This study used a
case-control design. Study samples were patients at Dr. Sardjito General
Hospital Yogyakarta between January 2014 until April 2015. Inclusion criteria
for the case group were sensorineural hearing loss (SNHL), and aged 0-5 years,
while the control group was normal hearing children. Exclusion criterion for
both groups was incomplete data. Diagnostic criteria were based on Oto-Acoustic Emission (OAE) and
Brainstem Evoke Response Audiometry (BERA) results.There were 31 samples in the case group and 31
samples in the control group.Results:Bivariate statistical analysis showed that
the TORCH (Toxoplasma Rubella Cytomegalovirus Herpes) variable was a
significant risk factor for SNHL (OR 11.94; 95% CI: 2.41-59.02), while hyperbilirubinemia (OR:
0.75; 95% CI: 0.26-2.14), low birth weight (OR: 2.36; 95% CI: 0.81-6.91), neonatal asphyxia (OR: 2.28; 95% CI: 0.94-8.47),
and prematurity (OR: 1.70; 95% CI: 0.52-5.55) were not significant risk
factors.Bivariate statistical analysis showed that the TORCH (Toxoplasma
Rubella Cytomegalovirus Herpes)
variable was a significant risk factor for SNHL (OR 11.94; 95% CI: 2.41-59.02).Based
on multivariate analysis we found TORCH infection was a significant risk factor
for the incidence of SNHL in children (OR 15.63;
95% CI: 2.84-85.95). Conclusions:Based on the results of this study, TORCH infection is a statistically significant
risk factor for the incidence of sensorineural hearing loss in children. Early screening for at-risk children is highly
recommended.
How to cite this paper
The Toxoplasma Rubella Cytomegalovirus Herpes (Torch) Infection Risk Factor of Sensorineural Hearing Loss in Children
Bambang Udji Djoko Rianto1*, Bondan Herwindo1, Anggoro Eka Raditya1, Ashadi Prasetyo1
1Department of Ear Nose Throat-Head and Neck Surgery, Faculty of Medicine, Universitas Gadjah Mada/ DR. Sardjito General Hospital
Yogyakarta, Indonesia
*Corresponding to: Bambang Udji Djoko Rianto, Department of Ear Nose Throat-Head and Neck Surgery, Faculty of Medicine, Universitas Gadjah Mada/ DR. Sardjito General Hospital Yogyakarta, Indonesia
How to cite this paper: Bambang Udji Djoko Rianto, Bondan Herwindo, Anggoro Eka Raditya, Ashadi Prasetyo1 (2017) The Toxoplasma Rubella Cytomegalovirus Herpes (Torch) Infection Risk Factor of Sensorineural Hearing Loss in Children. International Journal of Clinical and Experimental Medicine Research, 1(3), 16-21.
http://dx.doi.org/10.26855/ijcemr.2017.03.001
DOI: 10.26855/ijcemr.2017.03.001