² Department of Traditional Chinese Medicine First Affiliated Hospital of Air Force Military Medical University, the Army Medical Center in Traditional Chinese Medicine, Shaanxi, Xi'an 710032, China.

³ Shaanxi Traditional Chinese Medicine Hospital, Shaanxi, Xi'an 710003, China.

*Corresponding author: Jing Ma

Published: December 4,2020

Abstract

Objective: A Meta-analysis was used to systematically evaluate the efficacy and safety of Tianma gouteng decoction and Qiju dihuang pills in the treat-mennt of essential hypertension (EH). Methods: Randomized controlled trials (RCTs) associated with the treatment of EH via the Tianma gouteng gecoction combined with Qiju dihuang pills were searched on VIP, CNKI, Wanfang, PubMed, Cochrane Library databases from the clinical trials published from 2012 to October 2020. After the quality evaluation of literatures, the valid data from the literatures were extracted and Meta-analysis was carried out by using Review Manger 5.4 software. Results: There were 23 Chinese articles, in-cluding 2339 EH patients. The results of a Meta-analysis showed that, com-pared with western medicine treatment, traditional Chinese medicine combined with western medicine has better clinical [OR=4.48, 95%CI(2.72, 7.37), P<0.00001], In addition, solely traditional Chinese medicine treatment in contrast to western medicine improved the total clinical effective rate [OR = 9.73,95% CI(5.90, 16.06), P<0.00001]. Conclusion: Tianma gouteng decoc-tion combined with Qiju dihuang pills have a positive effect on the treatment of EH, and also show less toxic. Yet, considering the quality limitation of the literatures included, further high-quality clinical trials are needed be carried out to validate this conclusion.

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How to cite this paper

A Meta-analysis of Tianma Gouteng Decoction Combined with Qiju Dihuang Pills in the Treatment of Essential Hypertension

How to cite this paper: Xuexue Zhang, Jing Ma, Liangyu Cui, Hang Xu, Chengming Jia. (2020) A Meta-analysis of Tianma Gouteng Decoction Combined with Qiju Dihuang Pills in the Treatment of Essential Hypertension. International Journal of Clinical and Experimental Medicine Research, 4(4), 278-286.

DOI: http://dx.doi.org/10.26855/ijcemr.2020.10.026

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A Meta-analysis of Tianma Gouteng Decoction Combined with Qiju Dihuang Pills in the Treatment of Essential Hypertension

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