Xin Wang, Yuanyuan Zhang*
Department of Endocrinology, Shaanxi Provincial People's Hospital, 256 Youyi West Road, Xi'an, China.
*Corresponding author: Yuanyuan Zhang
Abstract
Objective: To study the clinical effect of insulin glargine in the treatment of elderly patients with type 2 diabetes mellitus complicated with critical medical patients. Methods: 100 elderly patients with type 2 diabetes mellitus complicated with medical critical illness in our hospital from February 2020 to February 2021 were selected retrospectively. According to the treatment methods, they were divided into two groups: neutral low protamine zinc human insulin single treatment group (single treatment group), neutral low protamine zinc human insulin combined with insulin glargine treatment group (combined treatment group), 50 cases in each group blood glucose level, serum C-peptide level and incidence of hypoglycemia. Results: The blood glucose concentration of the combined treatment group was lower than that of the single treatment group on 1D, 3D and 5D after treatment (P < 0.05), but there was no significant difference between the two groups before treatment, 7d and 10d after treatment (P > 0.05). After treatment, the fasting blood glucose, 2 h postprandial blood glucose and glycosylated hemoglobin of the combined treatment group were lower than those of the single treatment group (P < 0.05). After treatment, the levels of fasting C-peptide and postprandial 2H C-peptide in the combined treatment group were higher than those in the single treatment group (P < 0.05). The incidence of hypoglycemia in the combined treatment group was 10.00% (5/50), which was lower than 52.00% (26/50) in the single treatment group (P < 0.05). Conclusion: The clinical effect of insulin glargine in the treatment of elderly patients with type 2 diabetes mellitus complicated with critical medical patients is good.
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How to cite this paper
Clinical Study of Insulin Glargine in the Treatment of Elderly Patients with Type 2 Diabetes Mellitus Complicated with Critical Medical Patients
How to cite this paper: Xin Wang, Yuanyuan Zhang. (2021) Clinical Study of Insulin Glargine in the Treatment of Elderly Patients with Type 2 Diabetes Mellitus Complicated with Critical Medical Patients. International Journal of Clinical and Experimental Medicine Research, 5(3), 344-348.
DOI: http://dx.doi.org/10.26855/ijcemr.2021.07.017