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International Journal of Clinical and Experimental Medicine Research

ISSN Online: 2575-7970 ISSN Print: 2575-7989 CODEN: IJCEMH
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ArticleOpen Access http://dx.doi.org/10.26855/ijcemr.2026.03.016

Efficacy and Safety of Paravertebral Ozonated Water Injection Combined with Spinal Nerve Root Radiofrequency Ablation in the Treatment of Postherpetic Neuralgia

Li Wang*, Jiasong Wang, Lixiang Li, Minghui Li

Pain Department of Fuyang Women and Children's Hospital, Fuyang 236000, Anhui, China.

*Corresponding author: Li Wang

Published: March 31,2026

Abstract

Objective: To evaluate the efficacy and safety of paravertebral ozonated water injection combined with spinal nerve root radiofrequency ablation in the treatment of postherpetic neuralgia. Methods: A total of 80 patients with postherpetic neuralgia admitted to our hospital from July 2023 to July 2025 were enrolled and randomly divided into two groups (n = 40 each) using a random number table method. The control group received spinal nerve root radiofrequency ablation alone, while the study group received paravertebral ozonated water injection combined with spinal nerve root radiofrequency ablation. Pain scores and sleep disturbance scores at different time points before and after treatment were compared between the two groups, and complications were recorded. Results: At 2 weeks, 4 weeks, and 3 months after treatment, both pain scores and sleep disturbance scores in the two groups were significantly reduced compared with those before treatment. Moreover, the scores at all post-treatment time points in the study group were lower than those in the control group. The incidence of complications in the study group was also lower than that in the control group, with statistically significant differences (P < 0.05). Conclusion: For patients with postherpetic neuralgia, paravertebral ozonated water injection combined with spinal nerve root radiofrequency ablation can significantly alleviate postoperative pain and reduce the severity of sleep disturbances, demonstrating high treatment safety and favorable therapeutic efficacy.

Keywords

Paravertebral ozonated water injection; spinal nerve root radiofrequency ablation; combination therapy; postherpetic neuralgia

References

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How to cite this paper

Efficacy and Safety of Paravertebral Ozonated Water Injection Combined with Spinal Nerve Root Radiofrequency Ablation in the Treatment of Postherpetic Neuralgia

How to cite this paper: Li Wang, Jiasong Wang, Lixiang Li, Minghui Li. (2026) Efficacy and Safety of Paravertebral Ozonated Water Injection Combined with Spinal Nerve Root Radiofrequency Ablation in the Treatment of Postherpetic Neuralgia. International Journal of Clinical and Experimental Medicine Research10(2), 143-146.

DOI: http://dx.doi.org/10.26855/ijcemr.2026.03.016