Conception and Evaluation of a Biopolymer Cream Extracted from a Marine Biomass—Anti-Infectious Effect and Healing of Chronic Wounds

¹Laboratory of Functional Analysis of Chemical Processes (LFACP), Process Engineering Department, Faculty of Technology, University of Blida, Blida, Blida Province, Algeria.

²Loboratory of Energy Applications of Hydrogen, University Saad Dahlab of Blida 1, P.O. Box 270, 09000, Blida, Blida Province, Algeria.

³Biological Department, Faculty of Science of the Nature and the Life, University of Djilali Bounaam, Khemis Miliana, Algeria.

*Corresponding author: Laribi-Habchi Hassiba

Published: November 4,2021

Abstract

Antibiotic resistance is a threat to global health. This growing microbial resistance could kill millions of people. Chronic wounds prone to colonization by infectious pathogens that are difficult to treat because they develop in biofilms. In this context, an organic galenic formulation has enabled the development of an anti-infectious and healing cream based on an active principle, Beta chitosan with a degree of deacetylation of 70% and a molecular weight of 65 KDa extracted. Beta chitin from the bone of Sepia officinalis from the Mediterranean Sea in Algeria using shea butter, sweet almond oil and beeswax as excipients. The studied parameters of the cream, the antimicrobial evaluations, the rheological tests carried out as well as the preclinical tests carried out on animals with deep wounds caused by burns produced satisfactory results after 7 days of treatment compared to a cream conventional (21 days). Proven effectiveness can be sold at a lower cost compared to healing and antimicrobials.

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How to cite this paper

Conception and Evaluation of a Biopolymer Cream Extracted from a Marine Biomass—Anti-Infectious Effect and Healing of Chronic Wounds

How to cite this paper: Laribi-Habchi Hassiba, Saadoune Zineb, Amrouche Zoheir.(2021) Conception and Evaluation of a Biopolymer Cream Extracted from a Marine Biomass—Anti-Infectious Effect and Healing of Chronic Wounds. Advance in Biological Research, 2(1), 1-7.

DOI: http://dx.doi.org/10.26855/abr.2021.11.001

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Conception and Evaluation of a Biopolymer Cream Extracted from a Marine Biomass—Anti-Infectious Effect and Healing of Chronic Wounds

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