International Journal of Clinical and Experimental Medicine Research

ISSN Print: 2575-7989 Downloads: 113203 Total View: 1776946
Frequency: quarterly ISSN Online: 2575-7970 CODEN: IJCEMH
Email: ijcemr@hillpublisher.com
Article http://dx.doi.org/10.26855/ijcemr.2022.01.005

Clinical Observation of the Effect of Sevoflurane Inhalation Anesthesia on the Cardiac Function of Elderly Patients Based on Pulsifolex Platform

Zhipeng Liang1, Zheng Zuo1, Binque Wan1, Bingwei Hu2, Ying Hu2,*

1Department of Anesthesiology, Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang Province, 310007, China.

2Department of Anesthesiology, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang Province, 310012, China.

*Corresponding author: Ying Hu

Published: December 9,2021

Abstract

Objective: To investigate the effect of sevoflurane inhalation anesthesia on cardiac function of elderly patients based on pulsioflex platform.  Methods: from January 2017 to December 2019, 40 elderly patients scheduled for hip replacement were randomly divided into two groups: sevoflurane group (experimental group, n = 20) and propofol group (control group, n = 20).  Entropy index was used to maintain the depth of anesthesia in all patients.  Based on pulsioflex platform, the cardiac work index (CPI), left ventricular contractility index (dpmx), heart rate (HR) and blood pressure (BP) were recorded every 5 minutes before anesthesia, before operation and after operation until the end of operation.  The effects of sevoflurane inhalation anesthesia and propofol continuous infusion anesthesia on cardiac function of elderly patients were observed, and the anesthetic efficacy, changes of (CPI, dpmx, HR, BP) and reactions of the two groups were compared.  Results: the total effective rate of anesthesia in the observation group was 95.00%, and that in the control group was 90%.  The observation group was significantly higher than that in the control group (χ2 = 6.05, P = 0.01).  The experimental group was significantly higher than that in the control group, and the difference was statistically significant.  Before anesthesia, before operation and at the beginning of operation, the changes of cardiac work index (CPI), left ventricular systolic index (dpmx), heart rate (HR) and blood pressure (BP) in the experimental group were significantly higher than those in the control group, and the difference was statistically significant.  The two groups in the hemodynamics faster, hypotension, hypertension, heart rate too fast or too slow, myocardial ischemia signs and other adverse reactions, the experimental group were lower than the control group, the difference was not statistically significant (P > 0.05).  Conclusion: sevoflurane inhalation anesthesia has definite anesthetic effect on elderly patients undergoing hip replacement.  The impact of sevoflurane inhalation anesthesia on cardiac function (CPI, dpmx, HR, BP) of elderly patients monitored by pulsioflex platform is relatively large, and the adverse reactions are relatively small.

References

[1] Zhang Youhua, Li Xiebing. (2016). The value of cTnI, CK-MB in the diagnosis of acute myocardial infarction [J]. Fujian Journal of Medicine, 28(3): 48-53.

[2] Ye Ping’an, Liang Qi. (2013). The value of cardiac troponin I in the diagnosis of perioperative myocardial injury [J]. Chinese Journal of Anesthesiology, 15(2): 141-142.

[3] Riou, B. (2014). Troponin: important in severe trauma and a first step in the biological marker revolution [J]. Anesthesiology, 101: 1259-1260.

[4] Penttila, I., Penttila, K., Rantanen, T. (2016). Laboratory diagnosis of patients with acute chest pain [J]. Clin Chem Lab Med., 38: 187-97.

[5] Vijver, K. V. D., Pigozzi, C., Vervliet, L., et al. (2014). Validation of less-invasive hemodynamic monitoring with Pulsioflex in critically ill patients: interim results of a multicentre study [J]. Critical Care, 17(S2): 193-200.

[6] Salzwedel, C., Puig, J., Carstens, A., et al. (2015). Perioperative goal-directed hemodynamic therapy based on radial arterial pulse pressure variation and continuous cardiac index trending reduces postoperative complications after major abdominal surgery: a multi-center, prospective, randomized study [J]. Critical Care, 17(5): 192-198.

[7] Lee, T. H., Marcantonio, E. R., Mangione, C. M., et al. (2016). Derivation and prospective validation of a simple index for prediction of cardiac risk of major non-cardiac surgery [J]. Circulation, 100(10): 1043-1049.

[8] Butterworth, J., Furgerg, C. D. (2014). Improving cardiac outcomes after non-cardiac surgery [J]. Anesth Analg., 97(3): 613-615.

[9] Devereaux, P. J., Goldman, L., Yusuf, S., et al. (2018). Surveillance and prevention of major perioperative ischemic cardiac events in patients undergoing non-cardiac surgery: a review [J]. Can Med Assoc., 173(7): 779-7881.

[10] Kersten, J. R., Sehmeling, T., Tessmer, J., et al. (2019). Sevoflurane selectively increases coronary collateral blood flow independent of K-ATP channels in vivo. Anesthesiology, 90: 246-256.

[11] Conzen, P. F., Fischer, S., Detter, C., Peter, K. (2018). Sevoflurane provides greater protection of the myocardium than propofol in patients undergoing off-pump coronary artery bypass surgery [J]. Anesthesiology, 99: 826-833.

[12] Bein, B., Renner, J., Caliebe, D., et al. (2018). Sevoflurane but not propofol preserves myocardial function during minimally invasive direct coronary artery bypass surgery [J]. Anesth Analg., 100: 610-616.

How to cite this paper

Clinical Observation of the Effect of Sevoflurane Inhalation Anesthesia on the Cardiac Function of Elderly Patients Based on Pulsifolex Platform

How to cite this paper: Zhipeng Liang, Zheng Zuo, Binque Wan, Bingwei Hu, Ying Hu. (2022) Clinical Observation of the Effect of Sevoflurane Inhalation Anesthesia on the Cardiac Function of Elderly Patients Based on Pulsifolex Platform. International Journal of Clinical and Experimental Medicine Research6(1), 24-30.

DOI: http://dx.doi.org/10.26855/ijcemr.2022.01.005