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Latest Research Progress of the Pathogenesis of Depression and Its Status of TCM Treatment

Date: February 10,2022 |Hits: 4711 Download PDF How to cite this paper

Hesheng Zheng1, Yumei Wu2,*

1Shaanxi University of Traditional Chinese Medicine, Xianyang, Shaanxi, China.

2Fourth Military Medical University, Xi’an, Shaanxi, China.

*Corresponding author: Yumei Wu


Depressive disorder (DD) is one of the most common mental disorders and one of the main causes of disability in the world. Chronic or early life stress events are one of the main factors of DD. Recent studies have shown that the microbiota-gut-brain axis imbalance, the abnormal electrical activity of lateral habenula, and genetic variation are closely related to DD. Especially, in recent years, the emergence of the microbiota-gut-brain axis has attracted extensive attention. At present, the existing antidepressants and the therapeutic effect is not obvious even invalid for many patients, and it is likely to cause adverse effects. Traditional Chinese Medicine has obvious therapeutic effects, which are safe, reliable, low price, and significantly reduced the use of western medicine and its side effects. Therefore, traditional Chinese medicine and its therapeutic method gradually are applied to the clinical treatment of DD and achieved good results. The article summarizes the latest pathogenesis of DD and reviewed the mechanism of traditional Chinese medicine participating in DD treatment, to provide a reference for the clinical treatment of depression.


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How to cite this paper

Latest Research Progress of the Pathogenesis of Depression and Its Status of TCM Treatment

How to cite this paper: Hesheng Zheng, Yumei Wu. (2022) Latest Research Progress of the Pathogenesis of Depression and Its Status of TCM TreatmentInternational Journal of Clinical and Experimental Medicine Research6(1), 97-102.

DOI: http://dx.doi.org/10.26855/ijcemr.2022.01.016

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