Objective: Observing the efficacy of the self-made tonifying qi and Yin soup for recurrent oral ulcer. Methods: 32 patients with recurrent oral ulcer patients were treated with the self-made tonifying qi and Yin soup as the main side, and 4 weeks was 1 course of treatment, and the clinical effect was determined after 1 course of treatment. Results: (1) After 3 days of treatment of the self-made tonifying qi and Yin soup, 8 cases of the main clinical symptoms and signs were significantly reduced, and the main symptoms and symptoms after 5 days of treatment disappeared, that is, 8 cases of clinical recovery; After 5 days of treatment, 12 cases of main symptoms and symptoms were significantly reduced, that is, 12 cases of remarkable effect; After 5 days of treatment, 10 symptoms and signs were improved, that is, 10 effective cases; After 5 days of treatment, there were 2 cases of the main symptoms and signs disappeared without significant improvement, that is, 2 cases were ineffective. Therefore, after 1 course of treatment, 8 cases were recovered, 12 cases were remarkable effect, 10 cases were effective, 2 cases were ineffective, and the total effective rate was 93.75%. (2) The self-made tonifying qi and Yin soup can effectively reduce the number of ulcers, shorten ulcer diameter and reduce ulcer pain in patients with recurrent oral ulcer. Conclusion: The self-made tonifying qi and Yin soup in the treatment of recurrent oral ulcer has good clinical effect, which can significantly reduce ulcer pain, reduce the number of ulcer, shorten the diameter of ulcer, and significantly relieve the local symptoms of oral ulcer, which is worth further clinical promotion.
 Zhu Runqiu, Lin Xusheng, He Jiawei. (2020). Overview of the etiology of recurrent oral ulcers and the clinical treatment research [J]. Heilongjiang Medicine, 2020, 44(2): 287-288.
 Qianming Chen. (2012). Oral mucosal pathology [M]. Version 4, Beijing: People’s Health Press, 2012: 64-71.
 Ming Chen. (2012). Oral mucosal pathology [M]. 4, Version. Beijing: People's Health Publishing House, 2012: 64.
 Zheng Xiaoyu. (2002). Guiding Principles for Clinical Research of New Chinese Medicine [M]. Beijing: China Medical Science and Technology Press, 2002, 333.
 Zhu Lanying. (2019). Progress of TCM syndrome differentiation of recurrent oral ulcer [J]. Guangming Traditional Chinese Medicine, 2019, 34(14): 2272.
 Song Ye, Lin Dong, Mei Quanxi. (2019). Progress in chemical composition and pharmacological effects of Radix Radix larinae [J]. Chinese Pharmacist, 2019, 22(8): 1506-1509.
 Wang Xiaoqin, Su Kemeng. (2020). Progress in the chemical composition and pharmacological activity of North Salvia milti-orrhiza [J]. Chinese Modern Traditional Chinese Medicine, 2020, 22(3): 466-472.
 Wu Jiao, Wang Cong. (2018). Progress in the chemical composition and pharmacological effects of Astragalus sinensis [J]. Journal of Xinxiang Medical College, 2018, 35(9): 755-760.
 Wang Li, Xue Bing, Liang Shuang, Zhang Wenjun, et al. (2017). Progress in the pharmacological effects of Chuanknee [C]. China Conference, 2017: 256.
 Weng Lili, Chen Li, Su Ying, et al. (2018). Maternal chemical composition and pharmacological effects are known [J]. Jilin Traditional Chinese Medicine, 2018, 38(1): 90-92.
 Tao Ali, Jin Yaodong, Liu Jinqi, et al. (2013). Progress in the chemical composition, pharmacological action and clinical application of bletilla stria [J]. Jiangsu Agricultural Science, 2013, 41(11): 6-9.
 Chen, Ye. (2014). Progress in the chemical composition and pharmacological action of light bamboo leaves [J]. Asia-Pacific Traditional Medicine, 2014, 10 (13): 50-51.
 Zhang Yanli, Meng Fanjia, Pastoral, et al. (2019). Progress on the chemical composition and pharmacological effects of roasted licorice [J]. Chemical Engineer, 2019, (8): 60-62. So the curative effect is good.